県病薬会員病院からの学会発表紹介です。

県病薬会員病院から報告された論文紹介

2024年2月21日 17時37分

富山大学附属病院

1)Balo, R., Fernández, A. G., Chopdat, A., Ayadi, S. E., Kato, A., Estévez, R. J., Fleet, G. W. J., Estévez. J. C. Stable D-xylose ditriflate in divergent syntheses of dihydroxy prolines, pyrrolidines, tetrahydrofuran-2-carboxylic acids, and cyclic sugar b-amino acids. Org. Biomol. Chem. 20 (47) 9447-9459, 2023.

2)Zi, D., Song, Y.-Y., Lu, T.-T., Kise, M., Kato, A., Wang, J.-Z., Jia, Y.-M., Li, Y.-X., Fleet, G. W. J., Yu, C.-Y. Nanomolar β-glucosidase and β-galactosidase inhibition by enantiomeric α-1-C-alkyl-1,4-dideoxy-1,4-imino-arabinitol derivatives. Eur. J. Med. Chem. 247, 115056, 2023.

3)Zi, D., Shimadate, Y., Wang, J.-Z., Kato, A., Hou, Li, Y.-X., Jia, Y.-M., Fleet, G. W. J., Yu, C.-Y. Design, synthesis and glycosidase inhibition of DAB derivatives with C-4 peptide and dipeptide branches. Org. Biomol. Chem.21 (13) 2729-2741, 2023.

4)Yang, L.-F., Zhang, M., Shimadate, Y., Kato, A., Hou, T.-Y. L., Li, Y.-X., Jia, Y.-M., Fleet, G. W. J., Yu, C.-Y. Design and synthesis of iso-allo-DNJ and L-isoDALDP derivatives: pursuit of potent and selective inhibitors of α-glucosidase. Org. Biomol. Chem. 21 (16) 3453-3464, 2023.

5)Byatt, B., Kato, A., Pyne, S. (2023) Synthesis of the purported structure of glyphaeaside C and proposed revisions to the structures of the glyphaeaside alkaloids. J. Nat. Prod. 86 (5) 1261-1273, 2023.

6)Kato, A., Nakagome, I., Kise, M., Yoshimura, K., Tanaka, N., Nash, R. J., Fleet, G. W. J., Kobayashie Y., Ikeda, H., Okada, T., Toyooka, N. (2023) Design and pharmacological chaperone effects of N-(4’-phenylbutyl)-DAB derivatives targeting the lipophilic pocket of lysosomal acid a-glucosidase. J. Med. Chem. 66 (13) 9023-9039, 2023.

7)Désiré, J., Debbah, Z., Gueyrard, D., Marrot, J., Blériot, Y., Kato, A. Evaluation of nonnatural L-iminosugar C,C-glycosides, a new class of C-branched iminosugars, as glycosidase inhibitors. Carbohydr. Res. 532, 108903, 2023.