県病薬会員病院からの学会発表紹介です。

県病薬会員病院から報告された論文紹介

2026年2月14日 13時42分

富山大学附属病院

1)Gao, F.-T., Zhang, M., Shimadate, Y., Kato, A., Li, Y.-X., Jia, Y.-M., Yu, C.-Y. (2025) Enantiomeric C-6 fluorinated swainsonine derivatives as highly selective and potent inhibitors of α-mannosidase and α-L-rhamnosidase: design, synthesis and structure-activity relationship study. Eur. J. Med. Chem. 282, 117031.

2)Li, Y.-X., Zhang, M., Shimadate, Y., Kato, A., Wang, J.-Z., Jia, Y.-M., Fleet, G. W. J., Yu, C.-Y. (2025) C-2 Fluorinated castanospermines as potent and specific α-glucosidase inhibitors: synthesis and structure-activity relationship study. Org. Biomol. Chem. 23(12) 2854-2877.

3)Sanguankiattichai, N., Chandrasekar, B., Sheng, Y., Hardenbrook, N., Tabak, W. W. A., Drapal, M., Kaschani, F., Grünwald-Gruber, C., Krahn, D., Buscaill, P., Yamamoto, S., Kato, A., Nash, R., Fleet, G., Strasser, R., Fraser, P. D., Kaiser, M., Zhang, P., Preston, G. M., van der Hoorn., R. A. L. (2025) Bacterial pathogen deploys the iminosugar glycosyrin to manipulate plant glycobiology. Science 388 (6744) 297-303.

4)Tran, T. V., Marrot, J., Yamamoto, S., Yoshimura, K., Gillaizeau, I., Nicolas, C., Désiré, J., Kato, A., Auberger, N., Blériot, Y. (2025) Addition of lithiated 1,3 dithiane and nitronate to sugar-derived imines: synthesis of homoiminosugars and pipecolic acids analogs. Org. Lett. 27(20) 5068-5073.

5)Joachim, Q., Carry, D., Pasquale, M., Marrot, J., Yamamoto, S., Uziel, J., Kato, A., Lubin-Germain, N., Désiré, J., Ferry, A., Blériot, Y. (2025) Introduction of structural diversity at the C2 position of unsaturated iminosugars through palladium-catalysed cross-coupling reactions. Eur. J. Org. Chem. 28(32) e202500502.

6)Prichard, K., Yamamoro, S., Shimatate, Y., Yoshimura, K., Bartholomew, B., Gilbert, J., Sakoff, J., Nash, R., Kato, A., Simone, M. (2025) Borylated five-membered ring Iminosugars: synthesis, spectroscopic analysis and biological evaluation for glycosidase inhibition and anticancer properties for application in boron neutron capture therapy (BNCT) – Part 1. Pharmaceuticals 18(9) 1302.

7)Prichard, K., Yoshimura, K., Yamamoro, S., Taguchi, A., Bartholomew, B., Gilbert, J., Sakoff, J., Nash, R., Kato, A., Simone, M. (2025) Borylated 5-membered ring Iminosugars: synthesis, spectroscopic analysis and biological evaluation for glycosidase inhibition and anticancer properties for application in boron neutron capture therapy (BNCT) – Part 2. Pharmaceuticals 18(11) 1739.

公立南砺中央病院

鶴居勝也, 荒木遼太, 小川紗知, 讓原千広, 波多晶子, 中澤美樹子, 橋爪和恵, 窪田真弓, 栗原祥吾, 田口雅登:過疎地域の中規模公立病院における研究促進のための課題調査~大学協働による新たな多職種リカレント教育の試験的導入~,薬学教育,9e09048doi: 10.24489/jjphe.e090482025.